The Database of Randomised Controlled Trials in Diving and Hyperbaric Medicine
Welcome to the HBO Evidence pages.
Short critical appraisals of all randomised controlled trials and systematic reviews in both diving and hyperbaric medicine.
Original web authors: Dr. Dan Connor and A/Prof. Mike Bennett
For any technical queries or problems relating to this site, please contact the [
These appraisals are classified into disease categories and present the evidence in a standard way to enable rapid and meaningful comparisons between trials.
Pages written and maintained by The HBOE Working Group. This site is freely available to the public and professionals alike.
All enquiries:
Clinical Trials Network
Links to other related sites
We are always on the lookout for new trials or those we may have missed. If you know of any (human) RCTs in this area please contact us at
Evidence link: to evidence-based review of many HBOT indications (MD thesis of Mike Bennett)
Latest CATS
New evidence that HBO is effective for radiation cystitis (Oscarsson 2019), sudden hearing loss (Hu 2020)
Interesting findings that HBO seems to elevate mood when combined with rehabilitation following spinal cord injury (Feng 2017)
An abstract of a study that may show if diet can influence time to oxygen toxicity (Winstead-Derlega 2021)
More evidence that adding HBOT to good wound care helps heal diabetic foot ulcers (Kumar 2020) but unconvincing evidence that transcutaneous oxygen improves with the addition of HBOT (Wadee 2020)
Some further weak evidence that fibromyalgia may improve with HBOT (Izquierdo 2020 and Curtis 2021).
More pieces of the puzzle of dropping BSL in the chamber during treatment. HBO but not HB Air increases insulin sensitivity (Wilkinson 2020). Another suggests weak evidence for a benefit of adding HBO to radio-iodine oesophageal stents to treat cancer (Zhang 2020)
Papers awaiting appraisal: A list of published RCTs we have not got around to yet (take that as an invitation!).
Contributors to HBO Evidence appraisals in alphabetical order. Our thanks to all:
Mike Adams * Mike Bennett * Cecilia Bondjers * Alan Bourke * Kirsteen Brown * Tobias Cibis * Antonia Edge * Mark Fisher * Darran Foo * Abigail Fynn * Amy Gibbens * Mary Grealish * Glen Hawkins * Peter Hodkinson * Sean Hopson * James Hudgell *Brian Hui * Benjamin Kliot * Juliette Leverment * Hannah Rubinstein * Patrick Shiveley * Shamani Singham * David Smart * Sven Todd * Nick Titheridge * Michael Tom * Bosco Tran * Andre Venning * Annelies van der Hulst * Craig Wilson * Katherine Witheridge * Danielle Wood * Vincenzo Zanon
Whither 2023?
We are getting closer to escape velocity from this COVID stuff with a few signs of international meetings back on the agenda in 2022 (OK, so the UHMS was a super-spreader event. But who could have predicted that??).
The SPUMS Annual Scientific Meeting for 2023 is in glorious Cairns, Nth Queensland from 4th to 9th June. Check the SPUMS Website for details: Home | SPUMS
The UHMS ASM 2023 is planned for San Diego, California from 16th to 18th June: | UHMS web site
The EUBS ASM in 2022 is in Prague from 31st August to 3rd September . Check the meeting website: EUBS2020
Original web authors: Dr. Dan Connor and A/Prof. Mike Bennett
For any technical queries or problems relating to this site, please contact the [